News
2. August, 21

WP18 – Shared decision-making in glioblastoma patients – treatment decisions, patient involvement, and emotional well-being

Rationale

Shared decision making and the use of decision aids affect cancer patients’ experience of involvement, emotional well-being, and their experience of decision regret.

This correlation, however, has not yet been explored in patients with recurrent GBM. GBM patients differ from other cancer populations because of their neurological and cognitive challenges.

We hypothesize that shared decision can positively impact GBM patients and their families.

 
Objectives

  • Explore if there is a correlation between shared decision making and the experience of decision regret and emotional well-being (anxiety, depression) in GBM patients and their families.
  • Explore if there is a correlation between patients’ emotional well-being (anxiety, depression) and their preferences for decision-making involvement.

Approach

The study will be carried out as a national RCT study based on PRO-data. The randomization takes place on the clinician level.

The clinicians in the intervention group will be instructed on shared decision making and use a tailored decision aid recently developed at Odense University Hospital (not yet published) in their consultations with GBM patients when making treatment decisions. Clinicians in the control arm will carry on as usual.

GBM patients’ and their family members’ emotional well-being will be assessed using validated questionnaires at four different time points: before the decision-making consultation, immediately after the decision-making consultation, after two weeks, and after eight weeks. These data will be combined with measurements of decision involvement.


Endpoints

Patients’ and their family members’ experience of decision regret and emotional well-being (anxiety, depression) in relation to decision involvement.


Expected impact

We will generate new knowledge about the relations between emotional well-being, involvement preferences, and shared decision making in a GBM context. This knowledge will help tailor decision support to GBM patients and their families.